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Joint Pain, Stiffness & Repair

 

Recovery™ Repair For Joint Pain & Stiffness

• Prevents degeneration & joint pain at the “root” of the problem
• Reinforces membrane and matrix structures
• Hydrates & improves cell function
• Prevents the release of inflammation promoters
• Reduces bruising, excessive inflammation, spasm, joint stiffness, digestive abnormalities and respiratory distress

 

 

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Recovery™ for Joint Pain & Stiffness - Natural Pain Relief!

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JOINT PAIN, STIFFNESS & REPAIR - Information

• How joint pain begins
• How common is joint pain?
• What are the warning signs?
• How does joint pain progress?
• Indications of joint pain
• Pathophysiology, trauma, catabolism & disease
• Cell damge leads to
• Mechanism of action
• Ingredients
• Dosage & adminiatration

How Joint Pain Begins

• Known as "wear and tear" arthritis Caused by the gradual breakdown and loss of joint cartilage
• Ability to cushion the bones disappears, resulting in mild inflammation
• The bones that lie under the cartilage thicken, frequently forming spurs of bone that protrude into the joints
• It causes further distress to the joint resulting in aches and pains
• Most commonly affects hips, knees, hands and spine (neck and lower back)

How Common Is Joint Pain?

• Affects approximately one in 10 people in the USA and Canada, with most people developing the condition after the age of 45.
• Joint Pain known as arthritis is one of the most prevalent chronic health problems, second only to heart disease as a cause of work disability.
• Joint Pain limits daily activites such as walking, dressing, and bathing for over 7 million Americans.
• Baby boomers are now at prime risk. More then half those affected by joint pain are under the age of 65.
• Half of those Americans with joint pain don’t think anything can be done to help them. Are you one of them?

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What Are The Warning Signs?

The following are frequent joint pain symptoms:

• Joint pain, stiffness and swelling that lasts longer than two weeks
• Stiffness that tends to occur after periods of inactivity, such as sleeping or sitting
• Aching in the joints following activity (early symptom)
• A sensation of "grating" when the joint is used. (later symptom) Osteoarthritis symptoms
• Typically come on slowly, involving the area around the joints. Consult your doctor or other health care provider if you have persistent joint pain, stiffness or swelling that lasts for more than two weeks. The sooner joint pain symptoms are diagnosed the better your chances of curbing the disease's progression.
• If your joints are red, or feel hot or tender, you probably have a condition other than osteoarthritis and rheumatoid arthritis. Your doctor can provide you with a diagnosis and work with you to develop an osteoarthritis treatment plan.

How Does Joint Pain Progress?

Damage to the joints progresses slowly and may result in several problems.

• Pain, especially when moving a joint. Grating sound as the roughened cartilage at the ends of the bones rubs together.
• Stiff and/or sore, particularly after resting.
• Bumps and swellings may appear, especially on the fingers and feet.
• All these changes can make it difficult to move around and complete everyday tasks such as getting dressed, opening jars or climbing stairs.
• What Causes Joint Pain Symptoms?
• Inflammation is the body's natural response to being injured and is characterized by redness, swelling, heat and pain. When your joints become inflamed, you may experience any or all of these osteoarthritis symptoms. Inflammation can prevent the normal use of the joint and cause it to lose the ability to function properly.
• The key to reducing joint pain, and to halting joint pain progression through treatment, is controlling the inflammation that precedes the condition. Recovery with Nutricol was developed to manage joint pain symptoms, it works by curbing the inflammatory process.

Indications

Significant anti-inflammatory benefits indicate Recovery™ may be indicated as a primary option in the management of chronic inflammation and to imrove post-trauma rehabilitation.

aging, arthritis (osteo & rheumatoid), autoimmunity, back pain, bursitis, diabetes, eczema, fasciitis, fibromyalgia, osteoporosis, psoriasis, tendinitis, trauma rehabilitation, wound healing

The ability to decrease catabolism of cell structures associated with trauma and degenerative disease is what gives Recovery™ a potentially broad-spectrum indication profile. Results observed by clinicians over the last 10 years warrant further research for the treatment of chronicd skin, respiratory, gastrointestinal and autoimmune conditions.

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Pathophysiology

Trauma, Catabolism and Disease

When oxygen is utilized by the body, damaging “exhaust” called reactive oxygen species (ROS) are released. ROS include hydroxyl radicals, superoxides, hypochlorite and hydrogen peroxide, to name a few. Minimal amounts of ROS, play necessary roles in metabolism; whereas, when ROS production increases and the cell’s ability to neutralize ROS decreases, the overall effect on tissues is destructive (aging and disease). (1,4)

Increased cell production of ROS is linked to most degenerative conditions including heart disease, arthritis, cancer, periodontal disease, liver disease, cataracts, macular degeneration, diabetes, gastrointestinal diseases, autoimmunity and asthma. (5-7)

ROS react with cells initiating chain reactions that result in tissue damage causing inflammation, spasm, pain and disease. (1, 3)

Antioxidants, such as Coenzyme Q10, alpha lipoic acid and NADH (nicotinamide adenine dinucleotide) and anti-catabolic enzymes, such as glutathione peroxidase, superoxide dismutase and catalase minimize the damage due to ROS. Younger healthy cells produce larger quantities of protective substances. (3, 5)

Aging and disease result in diminished cell production of protective compounds leading to increased damage to cell membranes; inevitably, damage to membranes diminishes cellular ability to repair damaged tissue. (1, 7)

Membrane and extra-cellular matrix damage leads to decreased ideal first-intention healing involving parenchyma. (8-10)

Cell damage leads to:

1. Dehydration and Loss of Cell Function
   Decreased production of long chain glycosaminoglycans (GAG’s) with an increase in shorter chain GAG’s, resulting in dehydration of tissue and loss of membrane function (9, 11, 12)
2. Loss of Membrane Receptivity to Growth Factors
   Cell membrane desensitization to growth factors (somatomedins, insulin, etc.) necessary for cell repair, maintenance, protection
   and communication (13-15, 41)
3. Sclerosing of Tissue
   Deposition of heavily glycosylated, compact and infl exible collagen types V and VI (12, 16-22)
4. Compromised Ability to Heal
   Increased granulomatous second intention healing involving stromal elements (i.e. development of scar tissue) resulting in loss of cell/tissue function (9, 42)

Consequences:

Loss of cell and tissue function results in further inability to repair damage, leading to increased tendency to bruising, excessive inflammation, spasm, joint stiffness, digestive abnormalities and respiratory distress. (7, 9, 15, 20, 21, 23, 24)

* Insulin normally acts as a shuttle to drive amino acids, glucose, fatty acids, glucosamine and other precursors into the cell so that the cell may synthesize required structures for tissue repair.

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Mechanism of Action

Recovery™ is a functional food engineered to treat and prevent degeneration and inf ammation at the “root”. (43, 44)

Nutricol™, a potent proprietary bioflavonoid complex containing EGCG, proanthocyanidins, theaf avin and resveratrol from grapes and tea, is the primary active ingredient in Recovery™.

Nutricol™ reinforces membrane and matrix structures (halts damage that initiates infl ammatory and spasmodic reactions) (26, 27, 31, 45, 46)

Nutricol™ increases membrane receptivity to hormones such as insulin, IGF and thyroxine (required for anabolic repair/healing) (13, 14)

Site of Action

Nutricol™ embeds in the cell membrane and matrix. (43, 44, 48)

Mechanism of Action

The significant water and fat soluble antioxidant actions produce the following anti-catabolic and anti-infl ammatory effects:

1. Stabilize collagen aldimine reducible cross-links to reinforce the strength and elasticity of connective tissues such as cartilage, synovium, ligaments, tendons, fascia, bone, blood vessel walls and the dermis of the skin (26, 27)
2. Neutralize ROS and catabolic enzymes decreasing their negative impact on cellular and extra-cellular structure and function; this improves membrane receptivity to growth factors such as insulin, somatomedins and thyroxin required for anabolic repair and cell maintenance (4, 10 , 13, 28-30, 35, 49)
3. Decrease excess production of catabolic sustances such as collagenase, elastase, hyaluronidase, TNF, NOS and xanthine oxidase*; these substances are released from immune,
   microbial and damaged cells and cause damage to connective and epithelial tissue, resulting in joint pain, infl ammation, capillary fragility and other soft-tissue damage (4, 25, 31-35)
4. Prevent the release of infl ammation promoters such as histamine, serine proteases, prostaglandins and leukotrienes by non-competitively inhibiting the release of the proinflammatory enzymes cyclo-oxygenase, lipoxygenase and phosphodiesterase (33, 36)
5. Improve protective epithelial mucosal surface integrity (digestive, respiratory & genitourinary tract) (37-40) *Xanthine oxidase - enzyme that produces ROS. (4, 50)

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Ingredients

Nutricol™ 150mg
methyl sulfonyl methane 1,250mg
glucosamine hydrochloride 750mg
dimethylglycine 200mg
a proprietary bioflavonoid complex containing EGCG, theaflavin, proanthocyanidins and resveratrol from tea and grape.
In a base of vitamin C and fructo-oligosaccharides (watersoluble fiber).

*serving = 1 teaspoon powder or 5 vegetarian caps

 

Dosage and Administration

• Capsule form: 5 capsules twice daily or as directed by a health practitioner.
• Powder form: 1 teaspoon twice daily or as directed by a health practitioner. Powder form should be gradually increased in dose over a two week period (starting with 1/4 tsp per day and increasing dose by 1/4 tsp every 3 days until desired dose is achieved)
• Suggested use for children 12 and under (powder form): Introduce gradually over a two week period to a concentrated dose of 1/2 teaspoon per 20 lobs body weight. Mix with food, water or diluted juice. After 30 - 60 days it may be possible to reduce intake to 1/4 teaspoon per 20lbs body weight.

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